Brief Information of the Compound and Protein
Compound Name
2-methyl-6-[3-(1-phenylpiperidin-4-ylidene)prop-1-ynyl]pyridine
    Show/Hide
PubChem ID
CID: 25183826
SID: 57291557
Canonical SMILES
Cc1cccc(n1)C#CC=C1CCN(CC1)c1ccccc1
    Show/Hide
Compound Formula C20H20N2
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000308 T-REx-CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 55 nM
   TI
   LI
   LO
   TS
2
Ki = 29.2 nM
   TI
   LI
   LO
   TS