Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-[3-[1-(6-methyl-3-nitropyridin-2-yl)piperidin-4-ylidene]prop-1-ynyl]pyridine-3-carbonitrile
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 PubChem ID
CID: 122183738
Canonical SMILES
Cc1ccc(c(n1)N1CCC(CC1)=CC#Cc1ccc(cn1)C#N)[N+]([O-])=O
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Compound Formula C20H17N5O2
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000308 T-REx-CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 1.3 nM
   TI
   LI
   LO
   TS
2
Ki = 0.3 nM
   TI
   LI
   LO
   TS