Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-methyl-2-[(3E)-3-[3-(6-methylpyridin-2-yl)prop-2-ynylidene]piperidin-1-yl]-3-nitropyridine
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 PubChem ID
CID: 122183739
Canonical SMILES
Cc1cnc(N2CCC\C(C2)=C/C#Cc2cccc(C)n2)c(c1)[N+]([O-])=O
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Compound Formula C20H20N4O2
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000308 T-REx-CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 91 nM
   TI
   LI
   LO
   TS
2
Ki = 41.8 nM
   TI
   LI
   LO
   TS