Brief Information of the Compound and Protein
Compound Name
1-[4-(3-nitropyridin-2-yl)piperazin-1-yl]-3-phenylprop-2-yn-1-one
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PubChem ID
CID: 10382361
SID: 15397507
Canonical SMILES
[O-][N+](=O)c1cccnc1N1CCN(CC1)C(=O)C#Cc1ccccc1
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Compound Formula C18H16N4O3
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000308 T-REx-CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 0.9 nM
   TI
   LI
   LO
   TS
2
Ki = 0.5 nM
   TI
   LI
   LO
   TS