Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3,3-dimethyl-1-[4-[3-[1-(3-nitropyridin-2-yl)piperidin-4-ylidene]prop-1-ynyl]phenyl]azetidin-2-one
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 PubChem ID
CID: 57574931
Canonical SMILES
CC1(C)CN(C1=O)c1ccc(cc1)C#CC=C1CCN(CC1)c1ncccc1[N+]([O-])=O
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Compound Formula C24H24N4O3
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000308 T-REx-CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS