Brief Information of the Compound and Protein
Compound Name
1-(3-chlorophenyl)-3-[4-[2-[(2-methyl-6-piperazin-1-ylpyrimidin-4-yl)amino]-1,3-thiazol-5-yl]phenyl]urea
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PubChem ID
CID: 88876306
Canonical SMILES
Cc1nc(Nc2ncc(s2)-c2ccc(NC(=O)Nc3cccc(Cl)c3)cc2)cc(n1)N1CCNCC1
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Compound Formula C25H25ClN8OS
Compound Structure
Protein Name
Receptor-type tyrosine-protein kinase FLT3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P36888
Gene Name
FLT3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000071 MOLM-13 Homo sapiens (Human)  1
1
GI50 = 24 nM
   TI
   LI
   LO
   TS
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 20 nM
   TI
   LI
   LO
   TS