Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[2-(7-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-ethyl]-4-pyridin-2-yl-piperazine
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 PubChem ID
CID: 10948133
SID: 16001724
Canonical SMILES
COc1ccc2CCC(CCN3CCN(CC3)c3ccccn3)Cc2c1
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Compound Formula C22H29N3O
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 1A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P08908
Gene Name
HTR1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 3.548 nM
   TI
   LI
   LO
   TS
2
EC50 = 20.89 nM
   TI
   LI
   LO
   TS
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 0.16 nM
   TI
   LI
   LO
   TS