Brief Information of the Compound and Protein
Compound Name
1-[3-(5-Methoxy-3,4-dihydro-2H-naphthalen-1-ylidene)-propyl]-4-pyridin-2-yl-piperazine
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PubChem ID
CID: 10248163
SID: 15251281
Canonical SMILES
COc1cccc2\C(CCCc12)=C\CCN1CCN(CC1)c1ccccn1
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Compound Formula C23H29N3O
Compound Structure
Protein Name
5-hydroxytryptamine receptor 1A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P08908
Gene Name
HTR1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 2.951 nM
   TI
   LI
   LO
   TS
2
EC50 = 3388.44 nM
   TI
   LI
   LO
   TS
CL000017 HeLa Homo sapiens (Human)  1
1
Ki = 0.31 nM
   TI
   LI
   LO
   TS