Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(S)-3-(3,4-dichlorophenyl)-6-(3-(dimethylamino)pyrrolidine-1-carbonyl)-9H-carbazole-1-carboxamide
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 PubChem ID
CID: 66604791
Canonical SMILES
CN(C)[C@H]1CCN(C(=O)c2ccc3[nH]c4c(C(N)=O)cc(-c5ccc(Cl)c(Cl)c5)cc4c3c2)C1
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Compound Formula C26H24Cl2N4O2
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000224 SET-2
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 140 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3.1 nM