Brief Information of the Compound and Protein
Compound Name
7-(4-methylpiperazin-1-yl)-3-phenyl-9H-carbazole-1-carboxamide
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PubChem ID
CID: 66604274
Canonical SMILES
CN1CCN(CC1)c1ccc2c(c1)[nH]c1c(cc(cc21)-c1ccccc1)C(N)=O
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Compound Formula C24H24N4O
Compound Structure
Protein Name
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000224 SET-2 Homo sapiens (Human)  1
1
IC50 = 370 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2.1 nM