Brief Information of the Compound and Protein
Compound Name
N-(2-(5-chloro-2-(tetrahydro-2H-pyran-4-ylamino)pyrimidin-4-ylamino)phenyl)propionamide
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PubChem ID
CID: 122181361
Canonical SMILES
CCC(=O)Nc1ccccc1Nc1nc(NC2CCOCC2)ncc1Cl
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Compound Formula C18H22ClN5O2
Compound Structure
Protein Name
Mitogen-activated protein kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
>
CMGC protein kinase MAPK family
>
CMGC protein kinase ERK subfamily
Uniprot ID
P28482
Gene Name
MAPK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000045 A-375 Homo sapiens (Human)  1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 480 nM
2 IC50 = 4000 nM