Brief Information of the Compound and Protein
Compound Name
 Compound Info 
ULIXERTINIB
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 PubChem ID
CID: 11719003
SID: 16824058
Canonical SMILES
CC(C)Nc1cc(-c2c[nH]c(C(=O)N[C@H](CO)c3cccc(Cl)c3)c2)c(Cl)cn1
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Compound Formula C21H22Cl2N4O2
Compound Structure
Protein Name
 Protein Info 
Mitogen-activated protein kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
>
CMGC protein kinase MAPK family
>
CMGC protein kinase ERK subfamily
Uniprot ID
P28482
Gene Name
MAPK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000045 A-375
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 31 nM
   TI
   LI
   LO
   TS
2
IC50 = 4100 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.03 nM
2 IC50 < 0.3 nM
3 IC50 = 10.6 nM
4 Kd = 0.3162 nM
5 Kd = 10 nM
6 Ki = 0.04 nM