Brief Information of the Compound and Protein
Compound Name
6-[(2R)-2-(3-fluorophenyl)pyrrolidin-1-yl]-3-pyridin-2-ylimidazo[1,2-b]pyridazine
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PubChem ID
CID: 122179546
Canonical SMILES
Fc1cccc(c1)[C@H]1CCCN1c1ccc2ncc(-c3ccccn3)n2n1
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Compound Formula C21H18FN5
Compound Structure
Protein Name
Tyrosine-protein kinase receptor Tie-1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Tie family
Uniprot ID
P35590
Gene Name
TIE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
IC50 = 6500 nM
   TI
   LI
   LO
   TS