Brief Information of the Compound and Protein
Compound Name
1-(3,3-Dimethylbutyl)-3-(2-fluoro-4-methyl-5-(7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl)phenyl)urea
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PubChem ID
CID: 71721540
Canonical SMILES
CNc1ncc2cc(-c3cc(NC(=O)NCCC(C)(C)C)c(F)cc3C)c(C)nc2n1
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Compound Formula C23H29FN6O
Compound Structure
Protein Name
Mitogen-activated protein kinase kinase kinase kinase 5
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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STE protein kinase group
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STE protein kinase STE20 family
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STE protein kinase KHS subfamily
Uniprot ID
Q9Y4K4
Gene Name
MAP4K5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000045 A-375 Homo sapiens (Human)  1
1
IC50 = 970 nM
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