Brief Information of the Compound and Protein
Compound Name
 Compound Info 
PLX-4032
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 PubChem ID
CID: 42611257
SID: 123055406
Canonical SMILES
CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(cc23)-c2ccc(Cl)cc2)c1F
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Compound Formula C23H18ClF2N3O3S
Compound Structure
Protein Name
 Protein Info 
RAF proto-oncogene serine/threonine-protein kinase
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase RAF family
Uniprot ID
P04049
Gene Name
RAF1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000045 A-375
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 48 nM
2 IC50 = 128 nM
3 IC50 = 135 nM
4 IC50 = 410 nM