Brief Information of the Compound and Protein
Compound Name
8-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
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PubChem ID
CID: 5268
SID: 14902387
Canonical SMILES
O=C1NCN(c2ccccc2)C11CCN(CC2COc3ccccc3O2)CC1
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Compound Formula C22H25N3O3
Compound Structure
Protein Name
Nuclear receptor subfamily 1 group I member 2
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 1
>
Nuclear hormone receptor subfamily 1 group I
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Nuclear hormone receptor subfamily 1 group I member 2
Uniprot ID
O75469
Gene Name
NR1I2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000514 DPX2 Homo sapiens (Human)  2
1
EC50 = 20000 nM
   TI
   LI
   LO
   TS
2
EC50 = 35500 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 25100 nM