Brief Information of the Compound and Protein
Compound Name
3-[5-[(4S,6S)-2-amino-6-(3,5-dimethyl-1,2-oxazol-4-yl)-4-methyl-5,6-dihydro-1,3-thiazin-4-yl]-2,4-difluorophenyl]pyridine-2-carbonitrile
    Show/Hide
PubChem ID
CID: 90253319
Canonical SMILES
Cc1noc(C)c1[C@@H]1C[C@](C)(N=C(N)S1)c1cc(c(F)cc1F)-c1cccnc1C#N
    Show/Hide
Compound Formula C22H19F2N5OS
Compound Structure
Protein Name
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000008 H4 Homo sapiens (Human)  1
1
IC50 = 87 nM
   TI
   LI
   LO
   TS