Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-methyl-3-[2-(4-methylsulfonylphenyl)pyrimidin-4-yl]pyrrolo[2,3-c]pyridine
    Show/Hide
 PubChem ID
CID: 118735334
Canonical SMILES
Cn1cc(-c2ccnc(n2)-c2ccc(cc2)S(C)(=O)=O)c2ccncc12
    Show/Hide
Compound Formula C19H16N4O2S
Compound Structure
Protein Name
 Protein Info 
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
>
CMGC protein kinase DYRK family
>
CMGC protein kinase Dyrk1 subfamily
Uniprot ID
Q9Y463
Gene Name
DYRK1B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000109 COS-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
IC50 = 810 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 12 nM