Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-(1H-indol-3-yl)-N-[4-(4-methylpiperazin-1-yl)phenyl]pyrimidin-4-amine
    Show/Hide
 PubChem ID
CID: 118735321
Canonical SMILES
CN1CCN(CC1)c1ccc(Nc2cc(ncn2)-c2c[nH]c3ccccc23)cc1
    Show/Hide
Compound Formula C23H24N6
Compound Structure
Protein Name
 Protein Info 
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
>
CMGC protein kinase DYRK family
>
CMGC protein kinase Dyrk1 subfamily
Uniprot ID
Q9Y463
Gene Name
DYRK1B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000109 COS-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
IC50 = 9965 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 85 nM