Brief Information of the Compound and Protein
Compound Name
N-[4-(2-fluoropyridin-3-yl)phenyl]-5-morpholin-4-ylpentanamide
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PubChem ID
CID: 118735737
Canonical SMILES
Fc1ncccc1-c1ccc(NC(=O)CCCCN2CCOCC2)cc1
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Compound Formula C20H24FN3O2
Compound Structure
Protein Name
Neuronal acetylcholine receptor subunit alpha-7
Protein Classification
Ion channel
>
Ligand-gated ion channel
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Nicotinic acetylcholine receptor
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Nicotinic acetylcholine receptor alpha subunit
Uniprot ID
Q05941
Gene Name
CHRNA7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000029 GH4C1 Rattus norvegicus (Rat)  2
1
EC50 = 145 nM
   TI
   LI
   LO
   TS
2
EC50 = 27300 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 85 nM
   TI
   LI
   LO
   TS