Brief Information of the Compound and Protein
Compound Name
5-Morpholin-4-ylpentanoic acid(4-pyridin-3-ylphenyl)amide hydrochloride
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PubChem ID
CID: 45484303
Canonical SMILES
O=C(CCCCN1CCOCC1)Nc1ccc(cc1)-c1cccnc1
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Compound Formula C20H25N3O2
Compound Structure
Protein Name
Neuronal acetylcholine receptor subunit alpha-7
Protein Classification
Ion channel
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Ligand-gated ion channel
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Nicotinic acetylcholine receptor
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Nicotinic acetylcholine receptor alpha subunit
Uniprot ID
Q05941
Gene Name
CHRNA7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000029 GH4C1 Rattus norvegicus (Rat)  3
1
EC50 = 687 nM
   TI
   LI
   LO
   TS
2
EC50 = 1650 nM
   TI
   LI
   LO
   TS
3
EC50 = 42000 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  3
1
EC50 = 1650 nM
   TI
   LI
   LO
   TS
2
Ki = 500 nM
   TI
   LI
   LO
   TS
3
Ki = 670 nM
   TI
   LI
   LO
   TS