Brief Information of the Compound and Protein
Compound Name
N-(2-aminophenyl)-4-[[(4-pyridin-3-ylpyrimidin-2-yl)amino]methyl]benzamide
    Show/Hide
PubChem ID
CID: 9865515
SID: 14830272
Canonical SMILES
Nc1ccccc1NC(=O)c1ccc(CNc2nccc(n2)-c2cccnc2)cc1
    Show/Hide
Compound Formula C23H20N6O
Compound Structure
Protein Name
Histone deacetylase 2
Protein Classification
Epigenetic regulator
>
Eraser
>
Histone deacetylase
>
HDAC class I
Uniprot ID
Q92769
Gene Name
HDAC2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000023 BTI-Tn-5B1-4 Trichoplusia ni (Cabbage looper)  1
1
IC50 = 170 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 22 nM
2 IC50 = 280 nM
3 IC50 = 283 nM
4 IC50 = 290 nM
5 Ki = 32.4 nM