Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-(1H-indol-7-ylamino)-2-((1R,2S)-2-aminocyclohexylamino)pyrimidine-5-carboxamide
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 PubChem ID
CID: 118733756
Canonical SMILES
NC(=O)c1cnc(N[C@@H]2CCCC[C@@H]2N)nc1Nc1cccc2cc[nH]c12
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Compound Formula C19H23N7O
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase SYK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Syk family
Uniprot ID
P43405
Gene Name
SYK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000003 Ramos
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 170 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 94 nM