Brief Information of the Compound and Protein
Compound Name
6-(4-chloro-2-fluorophenyl)pyrimidine-4-carboxylic acid
    Show/Hide
PubChem ID
CID: 71282637
Canonical SMILES
OC(=O)c1cc(ncn1)-c1ccc(Cl)cc1F
    Show/Hide
Compound Formula C11H6ClFN2O2
Compound Structure
Protein Name
Kynurenine 3-monooxygenase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
O15229
Gene Name
KMO
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 1740 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 38 nM