Brief Information of the Compound and Protein
Compound Name
N-cyclopropyl-4-[6-(4-fluorophenoxy)-8-(oxan-4-ylmethylamino)imidazo[1,2-b]pyridazin-3-yl]benzamide
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PubChem ID
CID: 118732122
Canonical SMILES
Fc1ccc(Oc2cc(NCC3CCOCC3)c3ncc(-c4ccc(cc4)C(=O)NC4CC4)n3n2)cc1
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Compound Formula C28H28FN5O3
Compound Structure
Protein Name
Dual specificity protein kinase TTK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Other protein kinase group
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Other protein kinase TTK family
Uniprot ID
P33981
Gene Name
TTK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000305 RERF-LC-A1 Homo sapiens (Human)  1
1
IC50 = 7.8 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 5.6 nM