Brief Information of the Compound and Protein
Compound Name
N-cyclopropyl-4-[8-(oxan-4-ylmethylamino)-6-[(1,1,1-trifluoro-2-methylpropan-2-yl)amino]imidazo[1,2-b]pyridazin-3-yl]benzamide
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PubChem ID
CID: 66603863
Canonical SMILES
CC(C)(Nc1cc(NCC2CCOCC2)c2ncc(-c3ccc(cc3)C(=O)NC3CC3)n2n1)C(F)(F)F
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Compound Formula C26H31F3N6O2
Compound Structure
Protein Name
Dual specificity protein kinase TTK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Other protein kinase group
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Other protein kinase TTK family
Uniprot ID
P33981
Gene Name
TTK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000305 RERF-LC-A1 Homo sapiens (Human)  1
1
IC50 = 0.7 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2.8 nM