Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[(2S,3S)-3-hydroxy-2-methylpyrrolidin-1-yl]naphthalene-1-carbonitrile
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 PubChem ID
CID: 68710983
Canonical SMILES
C[C@H]1[C@@H](O)CCN1c1ccc(C#N)c2ccccc12
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Compound Formula C16H16N2O
Compound Structure
Protein Name
 Protein Info 
Androgen receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 4
Uniprot ID
P10275
Gene Name
AR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
EC50 = 0.25 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2.2 nM
2 IC50 = 2.4 nM