Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[3-(6-cyclopropyl-8-fluoro-1-oxoisoquinolin-2-yl)-2-(hydroxymethyl)phenyl]-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide
    Show/Hide
 PubChem ID
CID: 118729183
Canonical SMILES
CN(C)C(=O)c1cc2c(ncnc2[nH]1)-c1cccc(c1CO)-n1ccc2cc(cc(F)c2c1=O)C1CC1
    Show/Hide
Compound Formula C28H24FN5O3
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase BTK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Tec family
Uniprot ID
Q06187
Gene Name
BTK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000003 Ramos
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1560 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1357 nM