Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(+)-pilocarpine
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 PubChem ID
CID: 5910
SID: 15195683
Canonical SMILES
CC[C@H]1[C@@H](Cc2cncn2C)COC1=O
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Compound Formula C11H16N2O2
Compound Structure
Protein Name
 Protein Info 
Muscarinic acetylcholine receptor M1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Acetylcholine receptor
Uniprot ID
P11229
Gene Name
CHRM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000398 A-9
 Cell Line Info 
Mus musculus (Mouse)  1
1
EC50 = 8792 nM
   TI
   LI
   LO
   TS
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
EC50 = 831.76 nM
   TI
   LI
   LO
   TS
2
Kd = 2691.53 nM
   TI
   LI
   LO
   TS
3
Ki = 6606.93 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 17.5 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Kd = 2691.53 nM
2 Ki = 7943.28 nM