Brief Information of the Compound and Protein
Compound Name
5-[3-(6-pyrrolidin-1-ylpyrazin-2-yl)-1H-indol-5-yl]-1,3,4-thiadiazol-2-amine
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PubChem ID
CID: 90256983
Canonical SMILES
Nc1nnc(s1)-c1ccc2[nH]cc(-c3cncc(n3)N3CCCC3)c2c1
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Compound Formula C18H17N7S
Compound Structure
Protein Name
Serine/threonine-protein kinase pim-1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CAMK protein kinase group
>
CAMK protein kinase PIM family
Uniprot ID
P11309
Gene Name
PIM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS Homo sapiens (Human)  1
1
IC50 = 159 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 11 nM