Brief Information of the Compound and Protein
Compound Name
2-fluoro-5-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)benzonitrile
    Show/Hide
PubChem ID
CID: 118725477
Canonical SMILES
Fc1ccc(cc1C#N)-c1c[nH]c2ncnc(N3CCOCC3)c12
    Show/Hide
Compound Formula C17H14FN5O
Compound Structure
Protein Name
Leucine-rich repeat serine/threonine-protein kinase 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase LRRK family
Uniprot ID
Q5S007
Gene Name
LRRK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 2460 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 117 nM
2 IC50 = 920 nM