Brief Information of the Compound and Protein
Compound Name
6-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyridine-2-carbonitrile
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PubChem ID
CID: 72706839
Canonical SMILES
N#Cc1cccc(n1)-c1c[nH]c2ncnc(N3CCOCC3)c12
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Compound Formula C16H14N6O
Compound Structure
Protein Name
Leucine-rich repeat serine/threonine-protein kinase 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
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TKL protein kinase LRRK family
Uniprot ID
Q5S007
Gene Name
LRRK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 298 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 9 nM
2 IC50 = 26 nM