Brief Information of the Compound and Protein
Compound Name
8-Hydroxy-5-[(R)-1-hydroxy-2-(5,6-diethylindan-2-ylamino)-ethyl]-1H-quinolin-2-one
    Show/Hide
PubChem ID
CID: 6918554
SID: 15126362
Canonical SMILES
CCc1cc2CC(Cc2cc1CC)NC[C@H](O)c1ccc(O)c2[nH]c(=O)ccc12
    Show/Hide
Compound Formula C24H28N2O3
Compound Structure
Protein Name
Beta-1 adrenergic receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Adrenergic receptor
Uniprot ID
P08588
Gene Name
ADRB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 91 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 316.23 nM
2 Ki = 91.4 nM