Brief Information of the Compound and Protein
Compound Name
4-[4-(2-chlorophenyl)piperidin-1-yl]-1-(cyclopropylmethyl)-2-oxopyridine-3-carbonitrile
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PubChem ID
CID: 118714750
Canonical SMILES
Clc1ccccc1C1CCN(CC1)c1ccn(CC2CC2)c(=O)c1C#N
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Compound Formula C21H22ClN3O
Compound Structure
Protein Name
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
Q14416
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 = 49 nM
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