Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-({4-chloro-6-[(2,3-dimethylphenyl)amino]pyrimidin-2-yl}sulfanyl)acetic acid
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 PubChem ID
CID: 5694
SID: 12015627
Canonical SMILES
Cc1cccc(Nc2cc(Cl)nc(SCC(O)=O)n2)c1C
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Compound Formula C14H14ClN3O2S
Compound Structure
Protein Name
 Protein Info 
Peroxisome proliferator-activated receptor gamma
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group C
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Nuclear hormone receptor subfamily 1 group C member 3
Uniprot ID
P37231
Gene Name
PPARG
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  2
1
EC50 = 53700 nM
   TI
   LI
   LO
   TS
2
IC50 = 53700 nM
   TI
   LI
   LO
   TS
CL000063 Hep-G2
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 1600 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 29300 nM
2 Kd = 1297.3 nM
3 Kd = 1340 nM