Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(5-chloro-2-methylphenyl)-1-methyl-5-[2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]pyrrole-3-carboxamide
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 PubChem ID
CID: 76210601
Canonical SMILES
CN1CCN(CC1)c1ccc(Nc2nccc(n2)-c2cc(C(N)=O)c(-c3cc(Cl)ccc3C)n2C)cc1
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Compound Formula C28H30ClN7O
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000224 SET-2
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 250 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 22 nM