Brief Information of the Compound and Protein
Compound Name
2-fluoro-5-methyl-N-(4-(4-(morpholin-2-ylmethoxy)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)phenyl)benzenesulfonamide
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PubChem ID
CID: 118720602
Canonical SMILES
Cc1ccc(F)c(S(=O)(=O)Nc2ccc(-c3nc(OCC4CNCCO4)c4cn[nH]c4n3)cc2)c1
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Compound Formula C23H23FN6O4S
Compound Structure
Protein Name
Serine/threonine-protein kinase Sgk1
Protein Classification
Enzyme
>
Kinase
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Protein Kinase
>
AGC protein kinase group
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AGC protein kinase SGK family
Uniprot ID
O00141
Gene Name
SGK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS Homo sapiens (Human)  1
1
IC50 = 10 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 6.2 nM