Brief Information of the Compound and Protein
Compound Name
2-fluoro-N-(4-(4-((1r,4r)-4-hydroxycyclohexyloxy)-3-methyl-1H-pyrazolo[3,4-d]pyrimidin-6-yl)phenyl)-5-methoxybenzenesulfonamide
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Canonical SMILES
COc1ccc(F)c(S(=O)(=O)Nc2ccc(-c3nc(O[C@H]4CC[C@H](O)CC4)c4c(C)n[nH]c4n3)cc2)c1
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Compound Formula C25H26FN5O5S
Compound Structure
Protein Name
Serine/threonine-protein kinase Sgk1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase SGK family
Uniprot ID
O00141
Gene Name
SGK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS Homo sapiens (Human)  1
1
IC50 = 170 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 < 1.5 nM