Brief Information of the Compound and Protein
Compound Name
5-chloro-2-fluoro-N-(4-(4-((1r,4r)-4-hydroxycyclohexyloxy)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)phenyl)benzenesulfonamide
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Canonical SMILES
O=S(=O)(Nc1ccc(-c2nc(O[C@H]3CC[C@H](O)CC3)c3cn[nH]c3n2)cc1)c1cc(Cl)ccc1F
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Compound Formula C23H21ClFN5O4S
Compound Structure
Protein Name
Serine/threonine-protein kinase Sgk1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase SGK family
Uniprot ID
O00141
Gene Name
SGK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS Homo sapiens (Human)  1
1
IC50 = 120 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 < 1.5 nM