Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[4-(3-amino-4-cyclopropyl-2H-pyrazolo[3,4-d]pyrimidin-6-yl)phenyl]-2-cyano-5-methoxybenzenesulfonamide
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 PubChem ID
CID: 86268372
Canonical SMILES
COc1ccc(C#N)c(c1)S(=O)(=O)Nc1ccc(cc1)-c1nc(C2CC2)c2c(N)n[nH]c2n1
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Compound Formula C22H19N7O3S
Compound Structure
Protein Name
 Protein Info 
Serine/threonine-protein kinase Sgk1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase SGK family
Uniprot ID
O00141
Gene Name
SGK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 61 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 < 1.5 nM