Brief Information of the Compound and Protein
Compound Name
5-chloro-2-fluoro-N-[4-[4-(4-hydroxycyclohexyl)oxy-1H-pyrazolo[3,4-d]pyrimidin-6-yl]phenyl]benzenesulfonamide
    Show/Hide
PubChem ID
CID: 90421307
Canonical SMILES
OC1CCC(CC1)Oc1nc(nc2[nH]ncc12)-c1ccc(NS(=O)(=O)c2cc(Cl)ccc2F)cc1
    Show/Hide
Compound Formula C23H21ClFN5O4S
Compound Structure
Protein Name
Serine/threonine-protein kinase Sgk1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase SGK family
Uniprot ID
O00141
Gene Name
SGK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS Homo sapiens (Human)  1
1
IC50 = 670 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 < 1.2 nM