Brief Information of the Compound and Protein
Compound Name
N-[4-(3-amino-2H-pyrazolo[3,4-d]pyrimidin-6-yl)phenyl]-5-chloro-2-fluorobenzenesulfonamide
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PubChem ID
CID: 118720604
Canonical SMILES
Nc1n[nH]c2nc(ncc12)-c1ccc(NS(=O)(=O)c2cc(Cl)ccc2F)cc1
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Compound Formula C17H12ClFN6O2S
Compound Structure
Protein Name
Serine/threonine-protein kinase Sgk1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase SGK family
Uniprot ID
O00141
Gene Name
SGK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS Homo sapiens (Human)  1
1
IC50 = 390 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 19 nM