Brief Information of the Compound and Protein
Compound Name
3-[6-(2,5-dimethoxyphenyl)sulfanyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]-1,2-oxazole
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PubChem ID
CID: 118711391
Canonical SMILES
COc1ccc(OC)c(Sc2ccc3nnc(-c4ccon4)n3n2)c1
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Compound Formula C16H13N5O3S
Compound Structure
Protein Name
Leucine-rich repeat serine/threonine-protein kinase 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase LRRK family
Uniprot ID
Q5S007
Gene Name
LRRK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 4330 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 804 nM