Brief Information of the Compound and Protein
Compound Name
6-(5-chloro-2-methoxyphenyl)sulfanyl-3-(1-methylpyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazine
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PubChem ID
CID: 118711399
Canonical SMILES
COc1ccc(Cl)cc1Sc1ccc2nnc(-c3cnn(C)c3)n2n1
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Compound Formula C16H13ClN6OS
Compound Structure
Protein Name
Leucine-rich repeat serine/threonine-protein kinase 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase LRRK family
Uniprot ID
Q5S007
Gene Name
LRRK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 245 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 78 nM