Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-methoxy-3-[[3-(1-methylpyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]sulfanyl]benzonitrile
    Show/Hide
 PubChem ID
CID: 118711398
Canonical SMILES
COc1ccc(cc1Sc1ccc2nnc(-c3cnn(C)c3)n2n1)C#N
    Show/Hide
Compound Formula C17H13N7OS
Compound Structure
Protein Name
 Protein Info 
Leucine-rich repeat serine/threonine-protein kinase 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase LRRK family
Uniprot ID
Q5S007
Gene Name
LRRK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 2070 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 64 nM