Brief Information of the Compound and Protein
Compound Name
5-(2,5-dimethoxyphenyl)sulfanyl-2-methyl-3-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyrimidine
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PubChem ID
CID: 118711419
Canonical SMILES
COc1ccc(OC)c(Sc2ccn3nc(C)c(-c4cnn(C)c4)c3n2)c1
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Compound Formula C19H19N5O2S
Compound Structure
Protein Name
Leucine-rich repeat serine/threonine-protein kinase 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase LRRK family
Uniprot ID
Q5S007
Gene Name
LRRK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 759 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 110 nM