Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-(4-tert-butyl-3-hydroxyphenyl)-4-oxo-1H-quinoline-3-carboxamide
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 PubChem ID
CID: 57567374
Canonical SMILES
CC(C)(C)c1ccc(NC(=O)c2c[nH]c3ccccc3c2=O)cc1O
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Compound Formula C20H20N2O3
Compound Structure
Protein Name
 Protein Info 
Cystic fibrosis transmembrane conductance regulator
Protein Classification
Ion channel
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Other ion channel
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Chloride channel
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Cystic fibrosis transmembrane conductance regulator
Uniprot ID
P13569
Gene Name
CFTR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000805 HBE1
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 5 nM
   TI
   LI
   LO
   TS
CL000035 NIH 3T3
 Cell Line Info 
Mus musculus (Mouse)  1
1
EC50 = 3 nM
   TI
   LI
   LO
   TS