Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[5-[3-(6-cyclopropyl-8-fluoro-1-oxoisoquinolin-2-yl)-2-(hydroxymethyl)phenyl]-1-methyl-2-oxopyridin-3-yl]-4-(4-methylpiperazin-1-yl)benzamide
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 PubChem ID
CID: 118722851
Canonical SMILES
CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1cc(cn(C)c1=O)-c1cccc(c1CO)-n1ccc2cc(cc(F)c2c1=O)C1CC1
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Compound Formula C37H36FN5O4
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase BTK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Tec family
Uniprot ID
Q06187
Gene Name
BTK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000003 Ramos
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 > 5000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 818 nM