Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-cyclopropyl-8-fluoro-2-[2-methyl-3-[1-methyl-5-[[5-(4-methylpiperazin-1-yl)pyridin-2-yl]amino]-6-oxopyridin-3-yl]phenyl]isoquinolin-1-one
    Show/Hide
 PubChem ID
CID: 86342866
Canonical SMILES
CN1CCN(CC1)c1ccc(Nc2cc(cn(C)c2=O)-c2cccc(c2C)-n2ccc3cc(cc(F)c3c2=O)C2CC2)nc1
    Show/Hide
Compound Formula C35H35FN6O2
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase BTK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Tec family
Uniprot ID
Q06187
Gene Name
BTK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000003 Ramos
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 254 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 365 nM