Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[[4-chloro-3-[4-oxo-6-[4-(trifluoromethyl)phenyl]-3H-quinazolin-2-yl]phenyl]methyl]-2-methylpropanamide
    Show/Hide
 PubChem ID
CID: 137169017
Canonical SMILES
CC(C)C(=O)NCc1ccc(Cl)c(c1)-c1nc2ccc(cc2c(=O)[nH]1)-c1ccc(cc1)C(F)(F)F
    Show/Hide
Compound Formula C26H21ClF3N3O2
Compound Structure
Protein Name
 Protein Info 
Prostaglandin E synthase
Protein Classification
Enzyme
>
Isomerase
Uniprot ID
O14684
Gene Name
PTGES
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 55 nM
   TI
   LI
   LO
   TS